Correlation between Asthma Severity and Serum Vitamin D Levels: Experience from a Tertiary Care Centre in North India

Asthma is a chronic immunological disorder of the lungs characterized by reversible airway obstruction, airway inflammation, and increased airway hyper responsiveness in response to provocative challenges.

Objective: The aim of this study is to assess the level of serum vitamin D in patients with bronchial asthma and its correlation with disease severity.

Methods: The present study, included 120 patients diagnosed as bronchial asthma. The patients were grouped on the basis of vitamin D sufficiency and vitamin D levels were correlated with disease severity and lung function.

Results: Vitamin D deficiency was highly prevalent in asthmatic patients, and there was a direct and a significant relationship between serum vitamin D levels, severity of asthma, control of asthma, serum IgE levels, sputum eosinophils and lung function.

Conclusions: Measuring serum levels of vitamin D followed by supplementation could be considered in the routine assessment of patients with bronchial asthma.

Author(s):

Haider Guru, Sonaullah Shah, Roohi Rasool, Qurteeba Qadri, Faisal R Guru, Shumail Bashir and Syed Mehvish Yawar

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