SOX4 Gene Contributes in Induction of Uterine Adenomyosis

The objective of this study was to determine the level expression of SOX4 gene and its role in induce adenomyosis. Tissues specimens (30 patients and 10 healthy groups). Histological study of all tissues was carried out to observe the changes in tissues. Thirty biopsies of hysterectomy were concluded in this study. The expression levels of SOX4 gene were estimated by QRT-PCR. This study recorded the mean folding of SOX4 was a highly significant increased (p<0.01) in patients with adenomyosis (6.96 ± 0.27) when compared to the healthy control group (1.00 ± 0.00). We concluded the high expression of SOX4 gene had a role in development the uterine adenomyosis.

Author(s):

Mahdi Saber Al-Deresawi1* , Abdul Hussein Moyet AlFaisal2 , and Aseel Razaq Al-Rekabi2

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