Abstract

Treatment of Periapical Chronic Periodontitis Using Antifungal Drugs.

Aim: The aim of the investigation was to study some of the physicochemical properties and clinical trials of a paste based on zinc oxide with eugenol and an antifungal supplements (nistatine, fluconazole and “Narine”-lyophilized lacticoxide bacteria) for temporary filling of canals in endodontic treatment of chronic apical periodontitis. Materials and methods: A total of 74 patients were divided into 2 groups: group I included 54 patients with whom the composition of the paste was used as an antibacterial and antifungal agent zinc oxide (ZnO) antifungal preparation (nistatine, fluconazole and “Narine” lyophilized lactic-oxide bacteria, eugenol (clove oil), which was left in the root canal for 7 days, followed by filling with zinc-eugenol paste; group II included 20 patients, whose root canals were treate according to the described method, followed by filling a sealant paste based on zinc-eugenol paste (without an antifungal component). Results: The obtained results laboratory and clinical studies on show that the antifungal drugsfluconazole, nystatin, "Narine" have antibacterial and antifunga activity against. Taking into account the beneficial effect on the periapical tissues and the obtained data of laboratory studies allowed us to use the above mentioned drugs in the treatment of root canals and subsequent obturation with their introduction into the sealer. Conclusion: (The results obtained allow usto recommend a temporary endodontic paste based on zinc oxide with eugenol and an antifungal supplements (nistatine, fluconazole and “Narine”-lyophilized lactic-oxide bacteria) for temporary filling of canals in endodontic treatment of chronic apical periodontitis as an innovative method. Keywords: Chronic forms of apical periodontitis; Endodontic treatment; Antifungal therapeutic temporary; Rootfilling


Author(s):

Zhanna Khachatryan1 , Sona Hambardzumyan2 , Lyudmila Tatintsyan2 , GagikKhachatryan2 , Anna Hakobyan2 and Gagik Hakobyan2*



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